Surgeon experience affects perioperative pain in cats undergoing elective ovariohysterectomy: a randomized clinical trial

J Am Vet Med Assoc. 2024 Oct 16;262(12):1622-1631. doi: 10.2460/javma.24.05.0293. Print 2024 Dec 1.

Abstract

Objective: This study aimed to compare the outcomes between surgeries performed by either experienced or inexperienced surgeons by assessing intraoperative nociception and perioperative analgesia.

Methods: 16 healthy, client-owned female cats were randomly allocated into 2 groups of 8: one undergoing surgery by an experienced surgeon (GES group) and the other by inexperienced surgeons (GIS group). Both groups received IM premedication with acepromazine (0.05 mg/kg) and methadone (0.3 mg/kg). After 20 minutes, venipuncture and induction with propofol (dose-response, IV) were performed. Maintenance was achieved with inhaled isoflurane. Intraoperative vital parameters were monitored, and fentanyl (2.5 µg/kg, IV) was administered as rescue analgesia when needed. Postoperatively, pain was assessed with a visual analog scale and the multidimensional pain scale of the Universidade Estadual Paulista in Botucatu; morphine (0.2 mg/kg, IM) was used for rescue analgesia, as necessary.

Results: In the GIS group, significant increases in heart rate and systolic blood pressure were noted during surgery, especially during pedicle clamping. Respiratory rate and end-tidal isoflurane levels were higher in the GIS group at specific surgical stages. Survival analysis indicated that the GIS group had a greater need for fentanyl. Postoperative pain scores were generally low, but a higher proportion of GIS cats required rescue analgesia.

Conclusions: Surgeon experience influences intraoperative parameters and fentanyl consumption. Inexperienced surgeons contribute to increased postoperative pain and poorer wound healing outcomes in cats undergoing elective ovariohysterectomy.

Clinical relevance: Ovariohysterectomy is a common procedure in veterinary practice, and surgical expertise significantly impacts pain management and recovery. Yet, its effects have been underexplored, potentially compromising animal welfare.

Keywords: animal welfare; intraoperative nociception; ovariohysterectomy; perioperative analgesia; surgeon experience.

Publication types

  • Randomized Controlled Trial, Veterinary

MeSH terms

  • Animals
  • Cat Diseases / surgery
  • Cats / surgery
  • Clinical Competence
  • Female
  • Hysterectomy* / adverse effects
  • Hysterectomy* / veterinary
  • Ovariectomy* / adverse effects
  • Ovariectomy* / veterinary
  • Pain, Postoperative* / drug therapy
  • Pain, Postoperative* / prevention & control
  • Pain, Postoperative* / veterinary