Stand-alone transarterial flow diversion for treatment of carotid cavernous fistulas

J Stroke Cerebrovasc Dis. 2024 Dec;33(12):108047. doi: 10.1016/j.jstrokecerebrovasdis.2024.108047. Epub 2024 Oct 16.

Abstract

Objective: Carotid-cavernous fistulas (CCFs) are rare arteriovenous communications allowing blood to flow from the carotid artery into the cavernous sinus. Although currently coil and/or liquid embolization remain the preferred treatment methods for CCFs, flow diverters (FD) stents represent a viable alternative to traditional embolization techniques. This study explores both the technical aspects and rationale behind using FD stents as a stand-alone treatment approach for CCFs.

Methods: The study includes records of 7 patients with CCFs treated at two comprehensive stroke centers from 2019 to 2023. Patients treated with FD stenting in conjunction with coil and/or liquid embolization were excluded from the study.

Results: Five patients were diagnosed with direct CCFs and 2 patients with indirect CCFs. Six patients were treated with the Surpass Evolve FD stent and 1 patient with the Pipeline FD stent. DSA follow-up was performed for an average duration of 14.4 months following FD placement. Complete fistula obliteration with no residual shunting was observed in all patients. Furthermore, all patients experienced a complete resolution of symptoms following treatment.

Conclusions: The authors' experiences suggest the efficacy and safety of FD stenting as a stand-alone treatment option for CCFs. Compared to embolization, FD stents can better preserve the parent vessel and promote healing with less associated mass effect. Despite being a retrospective self-assessment with a relatively small sample size, to the authors' knowledge, this study represents the largest individual case series of patients with CCF treated with stand-alone FD stenting.

Keywords: Carotid cavernous fistula; Endovascular; Flow diversion; Pipeline embolization device; Surpass evolve.

Publication types

  • Multicenter Study

MeSH terms

  • Adult
  • Aged
  • Carotid-Cavernous Sinus Fistula* / diagnostic imaging
  • Carotid-Cavernous Sinus Fistula* / physiopathology
  • Carotid-Cavernous Sinus Fistula* / therapy
  • Embolization, Therapeutic / adverse effects
  • Embolization, Therapeutic / instrumentation
  • Endovascular Procedures* / adverse effects
  • Endovascular Procedures* / instrumentation
  • Female
  • Humans
  • Male
  • Middle Aged
  • Prosthesis Design
  • Retrospective Studies
  • Stents*
  • Time Factors
  • Treatment Outcome