Coma following ECT and intravenous droperidol: case report

J Clin Psychiatry. 1986 Feb;47(2):94-5.


A 60-year-old man with psychotic depression became comatose following the administration of intravenous droperidol given for post-ECT delirious agitation. The differential diagnosis, which included neuroleptic malignant syndrome and the possibility that droperidol may have uniquely detrimental effects in the context of post-ECT delirium, are discussed. In light of recent publications advocating droperidol as the pharmacologic treatment of choice for severe agitation, this case illustrates a need for greater caution in its use for the treatment of post-ECT delirium.

Publication types

  • Case Reports

MeSH terms

  • Coma / chemically induced*
  • Delirium / drug therapy*
  • Delirium / etiology
  • Depressive Disorder / therapy
  • Droperidol / adverse effects*
  • Electroconvulsive Therapy* / adverse effects
  • Humans
  • Male
  • Malignant Hyperthermia / diagnosis
  • Middle Aged
  • Neuroleptic Malignant Syndrome / diagnosis
  • Psychomotor Agitation / drug therapy
  • Psychomotor Agitation / etiology


  • Droperidol