Abstinence symptomatology and psychiatric diagnosis in cocaine abusers. Clinical observations

Arch Gen Psychiatry. 1986 Feb;43(2):107-13. doi: 10.1001/archpsyc.1986.01800020013003.


Abstinence symptoms and psychiatric diagnoses were evaluated in 30 chronic cocaine abusers. Structured diagnostic interviews were done within an experimental design intended to maximize differentiation of enduring symptoms from symptoms linked to binges of cocaine use. Longitudinal evaluations showed a three-phase sequence of post-cocaine abuse abstinence symptoms. Over half the sample also met criteria for ed 3 DSM-III, axis I psychiatric disorders. The findings present specific implications for treatment design.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Cocaine* / adverse effects
  • Conditioning, Psychological
  • Cues
  • Cyclothymic Disorder / diagnosis
  • Cyclothymic Disorder / psychology
  • Depressive Disorder / diagnosis
  • Depressive Disorder / psychology
  • Female
  • Humans
  • Male
  • Mental Disorders / diagnosis*
  • Mental Disorders / psychology
  • Psychiatric Status Rating Scales
  • Research Design / standards
  • Substance Withdrawal Syndrome / diagnosis*
  • Substance Withdrawal Syndrome / etiology
  • Substance Withdrawal Syndrome / psychology
  • Substance-Related Disorders / psychology*


  • Cocaine