Replacement of the anterior cruciate ligament using a patellar tendon allograft. An experimental study

J Bone Joint Surg Am. 1986 Mar;68(3):376-85.


The anterior cruciate ligament of twenty-five adult dogs was replaced using fresh or deep-frozen patellar-tendon allografts. The morphology of these transplanted allografts was then evaluated using routine histological studies and a vascular-injection (Spalteholz) technique at various intervals from two weeks to one year postoperatively. The fresh patellar-tendon allografts incited a marked inflammatory and rejection response which was characterized by perivascular cuffing and lymphocyte invasion. Deep-frozen patellar-tendon allografts appeared to be benign within the joint and underwent alterations that were comparable with those observed in autogenous patellar-tendon grafts. These included avascular necrosis followed by revascularization and cellular proliferation. At one year, the gross and histological appearance of the patellar tendon allograft resembled that of a normal anterior cruciate ligament.

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Dogs
  • Freezing
  • Graft Rejection
  • Graft Survival
  • Knee Joint / surgery*
  • Ligaments, Articular / surgery*
  • Patella*
  • Tendons / pathology
  • Tendons / transplantation*
  • Time Factors
  • Tissue Preservation / methods
  • Transplantation, Homologous