Brachial plexus injuries are the second most common perioperative peripheral nerve injuries. Malposition is a significant predisposing factor to these injuries. Additionally, some drugs, including tacrolimus, are known to predispose individuals to peripheral neuropathy. Herein, we present the electroneuromyography (EMG) findings within the first 48 hours for a patient who has been under tacrolimus treatment for five years due to liver transplantation and developed compression-induced reversible brachial plexopathy. Through this case, we highlighted that brachial plexus injury may not always result in axonal involvement and discussed the findings that may be encountered in early neurophysiological examinations.