Medulla oblongata edema associated with neurogenic pulmonary edema. Case report

J Neurosurg. 1986 Mar;64(3):494-500. doi: 10.3171/jns.1986.64.3.0494.


Neurogenic pulmonary edema (NPE) occurs in association with central nervous system disease without underlying cardiopulmonary problems. It is characterized by profound pulmonary vascular congestion and a fulminant clinical course. Although several reports document a role for experimental brain-stem lesions in the production of NPE, there have been only two studies in man correlating specific brain-stem lesions with NPE. The authors report a case of NPE occurring in a patient with von Hippel-Lindau disease and a dorsal medullary syrinx with postoperative dorsal medullary edema. The anatomical location of this patient's lesion is reviewed in the context of alternative theories of the pathogenesis of NPE.

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Brain Edema / complications*
  • Brain Edema / pathology
  • Brain Edema / surgery
  • Brain Neoplasms / surgery
  • Hemangiosarcoma / surgery
  • Humans
  • Male
  • Medulla Oblongata* / pathology
  • Pulmonary Edema / etiology*
  • Pulmonary Edema / pathology
  • Pulmonary Edema / surgery