A model for the kinetics of potassium in healthy humans

Phys Med Biol. 1986 Jan;31(1):23-42. doi: 10.1088/0031-9155/31/1/003.

Abstract

A model is developed to describe the distribution and excretion of potassium at arbitrary times during or after intake by ingestion or injection. The movement of K is tracked in greater detail than in previous models and is described in terms of anatomical compartments rather than the hypothetical, mathematically derived pools often considered. Parameter values are derived for a typical resting healthy adult male. Because of its anatomically realistic framework, the model may be used as a point of departure for modelling the behaviour of K in various subgroups of the population under less ideal conditions.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adult
  • Bone and Bones / metabolism
  • Digestive System / metabolism
  • Erythrocytes / metabolism
  • Humans
  • Kidney / metabolism
  • Kinetics
  • Lung / metabolism
  • Male
  • Models, Biological
  • Muscles / metabolism
  • Myocardium / metabolism
  • Potassium / metabolism*
  • Reference Values
  • Regional Blood Flow
  • Tissue Distribution

Substances

  • Potassium