The coincidence of glucose-6-phosphate dehydrogenase deficiency and hemoglobin S gene in Cukurova Province, Turkey

Am J Epidemiol. 1986 Apr;123(4):677-80. doi: 10.1093/oxfordjournals.aje.a114287.

Abstract

A total of 1,582 subjects from 10 villages of different ethnic populations were screened for glucose-6-phosphate dehydrogenase (G6PD) deficiency (GdB-, Mediterranean variant) and hemoglobin S gene, and the coincidence of both abnormalities was determined. Although the prevalence of both abnormalities was found to be highest in an Eti-Turk group living in the Tarsus area, coincidence was not significant. In a single village of Adana Eti-Turks, however, coincidence was found to be significant, although neither the frequency of G6PD deficiency nor the existence of hemoglobin S gene was highest in that village.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anemia, Sickle Cell / complications
  • Electrophoresis
  • Epidemiologic Methods
  • Ethnic Groups
  • Female
  • Glucosephosphate Dehydrogenase Deficiency / complications
  • Glucosephosphate Dehydrogenase Deficiency / epidemiology*
  • Hemoglobin, Sickle / genetics*
  • Humans
  • Male
  • Turkey

Substances

  • Hemoglobin, Sickle