40 Hz binaural beats entrainment enhances the mood and cognition of medical students

Int J Neurosci. 2026 Jan;136(1):24-36. doi: 10.1080/00207454.2024.2429495. Epub 2024 Nov 19.

Abstract

Background: Many medical students experience psychological distress from high academic demands, potentially harming their performance and mental health. Binaural beats (BB) stimulation, particularly gamma band entrainment, has been suggested to enhance neural communication, cognition, and reduce anxiety.

Objective: This study aimed to determine whether 40 Hz BB could improve cognitive performance and mood in medical students.

Method: Forty participants, selected based on the inclusion criteria of good health, normal hearing, and no mental illness were recruited considering factors such as all sessions availability and consent. Participants listened to BB for 15 min, three times a week, over three consecutive weeks. Electroencephalogram recordings confirmed that 40 Hz BB induced gamma neural oscillations in the brain. Emotional states were assessed using the 32-item Brunel Mood Scale (BRUMS) with ratings on a 5-point Likert scale, whereas cognitive function was measured with the Stroop's test, based on reaction time in milliseconds. Pre- and post-BB comparisons and gender-related differences were analyzed using paired and unpaired t-tests or appropriate non-parametric tests.

Result: Listening to BB significantly reduced negative emotions (p < 0.001), enhanced positive emotions (p < 0.001), and facilitated improvements in cognitive performance. However, the effects of BB were gender-specific, with female students showing greater improvements in 'happiness' and 'calmness', (p < 0.001), while males experienced more pronounced enhancements in cognitive performance (p < 0.001). Additionally, time-dependent effects of BB were also observed.

Conclusion: 40 Hz BB appears to be an effective tool for helping students manage their challenges calmly and more efficiently.

Keywords: BRUMS; Gamma binaural beats; Stroop’s test; cognition; emotion.

Plain language summary

Listening to 40-Hz binaural beats increases the gamma-band activity in the brain40-Hz binaural beats help to improve mood and cognitive performanceBinaural beats-mediated effects are based on the gender and the duration of auditory stimulus.

MeSH terms

  • Acoustic Stimulation* / methods
  • Adult
  • Affect* / physiology
  • Auditory Perception* / physiology
  • Cognition* / physiology
  • Electroencephalography
  • Female
  • Gamma Rhythm* / physiology
  • Humans
  • Male
  • Students, Medical* / psychology
  • Young Adult