Innovations in Hidradenitis Suppurativa

Dermatol Clin. 2025 Jan;43(1):35-53. doi: 10.1016/j.det.2024.08.003. Epub 2024 Oct 22.

Abstract

Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition characterized by painful, recurrent abscesses, inflammatory nodules, and draining tunnels. Biologic and small molecule therapeutics are effective for treatment of moderate-to-severe HS. The field of HS is rapidly growing with numerous ongoing clinical trials exploring novel agents. This review highlights the latest discoveries in the field of HS, with a particular focus on novel therapeutic agents and procedural management.

Keywords: Biologics; Hidradenitis suppurativa; Innovations; Small molecules.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Biological Products / therapeutic use
  • Dermatologic Agents / therapeutic use
  • Hidradenitis Suppurativa* / drug therapy
  • Hidradenitis Suppurativa* / therapy
  • Humans

Substances

  • Dermatologic Agents
  • Biological Products
  • Anti-Bacterial Agents