Alcohol enhances vitamin C excretion in the urine

Alcohol Alcohol. 1986;21(1):81-4.


Urinary ascorbic acid excretion was measured on four consecutive days in 9 normal male volunteers for 4 hr before and after drinking nothing (control), 0.58 g alcohol/kg body wt as whisky or lager or water (11./70 kg body wt). The normal reduction in ascorbic acid excretion under control conditions was abolished by drinking water. Alcohol in either form produced a 47% increase in urinary ascorbic acid excretion. A similar ascorbiuresis in chronic alcoholics would be an additional factor in the causation of vitamin C deficiency in these patients.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Alcohol Drinking*
  • Ascorbic Acid / blood
  • Ascorbic Acid / metabolism*
  • Ascorbic Acid / urine
  • Ethanol / pharmacology*
  • Humans
  • Kidney / metabolism*
  • Male


  • Ethanol
  • Ascorbic Acid