Abstract
Normal human plasma contains a fraction of very low density lipoprotein (VLDL) which, unlike most VLDL, contains no apolipoprotein E and, unlike apo-E-containing VLDL, is enriched in phosphatidylethanolamine. This fraction made up 0.28 +/- 0.09 of total VLDL triglyceride. Interconversion of the two isolated VLDL fractions was not detected during incubation (2 h, 37 degrees C) and they may represent the physical forms of apo-B corresponding to distinct metabolic pathways in plasma.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Apolipoproteins B / blood
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Apolipoproteins E / blood*
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Electrophoresis, Polyacrylamide Gel
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Humans
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Isoelectric Focusing
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Lipoproteins, LDL / blood
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Lipoproteins, VLDL / blood*
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Phosphatidylethanolamines / blood*
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Phospholipids / blood
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Triglycerides / blood
Substances
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Apolipoproteins B
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Apolipoproteins E
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Lipoproteins, LDL
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Lipoproteins, VLDL
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Phosphatidylethanolamines
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Phospholipids
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Triglycerides
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very low density lipoprotein triglyceride