GENTLE-PACE - A multicenter, randomized, double-blinded research study comparinG the Efficacy and safety of cardioNeuroablaTion vs. permanent pacing in patients with an implantabLE PACEmaker for symptomatic bradycardia

Przemysław Skoczyński; Bruno Hrymniak; Bartosz Skonieczny; Bartosz Biel; Krystian Josiak; Bartosz Krakowiak; Kuba Ptaszkowski; Krzysztof S Gołba; Jacek Bednarek; Jarosław Kosior; Edyta Stodółkiewicz-Nowarska; Anna Skotny; Patrycja Aktanorowicz; Agnieszka Andrejków; Anna Ratajska; Magdalena Zając; Waldemar Banasiak; Adrian Doroszko; Dorota Zyśko; Sebastian Stec; José Carlos Pachón-Mateos; Dariusz Jagielski

doi:10.5603/cj.100718

GENTLE-PACE - A multicenter, randomized, double-blinded research study comparinG the Efficacy and safety of cardioNeuroablaTion vs. permanent pacing in patients with an implantabLE PACEmaker for symptomatic bradycardia

Cardiol J. 2024 Nov 25. doi: 10.5603/cj.100718. Online ahead of print.

Authors

Przemysław Skoczyński^{1

2}, Bruno Hrymniak³, Bartosz Skonieczny¹, Bartosz Biel¹, Krystian Josiak¹, Bartosz Krakowiak¹, Kuba Ptaszkowski^{4

5}, Krzysztof S Gołba^{6

7}, Jacek Bednarek^{6

7}, Jarosław Kosior⁸, Edyta Stodółkiewicz-Nowarska⁹, Anna Skotny¹⁰, Patrycja Aktanorowicz^{1

11}, Agnieszka Andrejków¹¹, Anna Ratajska^{12

13}, Magdalena Zając¹⁴, Waldemar Banasiak^{1

15}, Adrian Doroszko^{1

15}, Dorota Zyśko^{1

15}, Sebastian Stec¹⁶, José Carlos Pachón-Mateos^{17

18}, Dariusz Jagielski^{1

15}

Affiliations

¹ Department of Cardiology, Center for Heart Diseases, 4th Military Hospital, Wroclaw, Poland.
² Department of Emergency Medicine, Wroclaw Medical University, Wroclaw, Poland.
³ Department of Cardiology, Center for Heart Diseases, 4th Military Hospital, Wroclaw, Poland. bruno.hrymniak@gmail.com.
⁴ Faculty of Health Sciences, Wroclaw Medical University, Wroclaw, Poland.
⁵ Regional Digital Medicine Center, 4th Military Hospital Wroclaw, Poland.
⁶ Department of Electrocardiology and Heart Failure, Medical University of Silesia, Katowice, Poland.
⁷ Department of Electrocardiology, Upper-Silesian Medical Center, Katowice, Poland.
⁸ Cardiology Department, Mazovian Specialty Hospital, Radom, Poland.
⁹ CardioMedicum, Krakow, Poland.
¹⁰ Harvard T.H. Chan School of Public Health - ECPE Boston, Boston, United States.
¹¹ Clinical Research Support Center, 4th Military Hospital, Wroclaw, Poland.
¹² Psychological Therapeutic and Research Centre, University Hospital No. 2 in Bydgoszcz, Poland.
¹³ Department of Humanization, Medicine and Sexology, Collegium Medicum, University of Zielona Góra, Poland.
¹⁴ Department of Special Pedagogy and Speech Therapy, Faculty of Pedagogy, Kazimierz Wielki University, Bydgoszcz, Poland.
¹⁵ Faculty of Medicine, Wrocław University of Science and Technology, Wroclaw, Poland.
¹⁶ Division of Electrophysiology, Cardioneuroablation, Catheter Ablation, and Cardiac Stimulation, Subcarpathian Center for Cardiovascular Intervention, Sanok, Poland.
¹⁷ São Paulo Heart Hospital, São Paulo, Brazil.
¹⁸ Dante Pazzanese Cardiology Institute, São Paulo, Brazil.

PMID: 39584414
DOI: 10.5603/cj.100718

No abstract available

Keywords: AVB; CNA; RCT; SND; atrioventricular block; cardioneuroablation; cardioneuromodulation; pacemaker; randomized clinical trial; sinus node dysfunction.