Behavior of mild cervical dysplasia during long-term follow-up

Obstet Gynecol. 1986 May;67(5):665-9. doi: 10.1097/00006250-198605000-00012.


Five hundred and fifty-five women with cervical cytologically diagnosed mild cervical dysplasia were followed by cytology without major treatment. Biopsies were performed in 14% resulting in no significant influence on the outcome of the studied material. Regression to normal occurred in 62% (follow-up 39 months), progression to severe dysplasia/carcinoma in situ/invasive carcinoma in 16% (invasive carcinoma: two patients), and persistence of dysplasia in 22%. Life table analysis calculated the risk of progression of mild dysplasia to be 250 to 800/100,000 women/year. A comparison with the incidence of carcinoma in situ, four of 100,000 women/year, illustrates the yearly risk for a woman with mild dysplasia as 560 times greater than for a woman without cervical dysplasia to develop severe dysplasia/carcinoma in situ/invasive carcinoma.

MeSH terms

  • Actuarial Analysis
  • Adolescent
  • Adult
  • Aged
  • Biopsy
  • Carcinoma in Situ / pathology
  • Cervix Uteri / pathology*
  • Colposcopy
  • Curettage
  • Female
  • Follow-Up Studies
  • Humans
  • Middle Aged
  • Neoplasm Invasiveness
  • Precancerous Conditions / pathology
  • Sweden
  • Uterine Cervical Neoplasms / pathology
  • Vaginal Smears