Early versus delayed timing of vitrectomy after open-globe injury

David McMaster; Sophia Halliday; Syeda F Hussain; Theofilos Kempapidis; Lana S Bush; Marcus Colyer; Scott F McClellan; Sarah Miller; Grant Justin; Rupesh Agrawal; Annette K Hoskin; Kara Cavuoto; James Leong; Andrés Manuel Rousselot Ascarza; Fasika A Woreta; John Cason; Kyle Miller; Matthew C Caldwell; William Gensheimer; Tom H Williamson; Felipe Dhawahir-Scala; Peter Shah; Andrew Coombes; Gangadhara Sundar; Robert Mazzoli; Malcolm Woodcock; Stephanie L Watson; Ferenc Kuhn; Renata S M Gomes; Richard J Blanch

doi:10.1002/14651858.CD016086

Early versus delayed timing of vitrectomy after open-globe injury

Cochrane Database Syst Rev. 2024 Nov 29;11(11):CD016086. doi: 10.1002/14651858.CD016086.

Authors

David McMaster¹, Sophia Halliday², Syeda F Hussain², Theofilos Kempapidis², Lana S Bush³, Marcus Colyer⁴, Scott F McClellan⁵, Sarah Miller⁶, Grant Justin^{7

8}, Rupesh Agrawal⁹, Annette K Hoskin^{10

11}, Kara Cavuoto¹², James Leong^{10

11}, Andrés Manuel Rousselot Ascarza¹³, Fasika A Woreta⁶, John Cason⁷, Kyle Miller^{7

14}, Matthew C Caldwell¹⁵, William Gensheimer^{16

17}, Tom H Williamson¹⁸, Felipe Dhawahir-Scala¹⁹, Peter Shah²⁰, Andrew Coombes²¹, Gangadhara Sundar²², Robert Mazzoli⁷, Malcolm Woodcock²³, Stephanie L Watson²⁴, Ferenc Kuhn^{25

26}, Renata S M Gomes^{2

27}, Richard J Blanch^{3

28

29}

Affiliations

¹ Imperial College London, London, UK.
² BRAVO VICTOR, London, UK.
³ Neuroscience and Ophthalmology, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK.
⁴ Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
⁵ Vision Center of Excellence, Research & Development Directorate (J-9), Defence Health Agency, MD, USA.
⁶ Wilmer Eye Institute, Johns Hopkins University School of Medicine, MD, USA.
⁷ Uniformed Services University of the Health Sciences, MD, USA.
⁸ Duke Eye Center, Duke University Hospitals, NC, USA.
⁹ National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, Singapore.
¹⁰ Save Sight Institute, The University of Sydney, Sydney, Australia.
¹¹ Lions Eye Institute, University of Western Australia, Perth, Australia.
¹² Bascom Palmer Eye Institute, University of Miami, Miama, FL, USA.
¹³ Consultorios Oftalmológicos Benisek-Ascarza, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina.
¹⁴ Department of Ophthalmology, Navy Medical Center Portsmouth, VA, USA.
¹⁵ Department of Ophthalmology, San Antonio Uniformed Services Health Education Consortium, San Antonio, Texas, USA.
¹⁶ White River Junction Veterans Administration Medical Center, White River Junction, VT, USA.
¹⁷ Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.
¹⁸ Department of Ophthalmology, St Thomas' Hospital, London, UK.
¹⁹ Manchester Royal Eye Hospital, Manchester, UK.
²⁰ Ophthalmology, University Hospital Birmingham NHS Foundation Trust, Birmingham, UK.
²¹ Department of Ophthalmology, The Royal London Hospital, London, UK.
²² Department of Ophthalmology, National University Hospital, Singapore, Singapore.
²³ Worcestershire Acute Hospitals NHS Trust, Worcester, UK.
²⁴ Sydney Eye Hospital, Sydney, Australia.
²⁵ Department of Ophthalmology, University of Pécs Medical School, Pécs, Hungary.
²⁶ Helen Keller Foundation for Research and Education, AL, USA.
²⁷ Northern Hub for Veterans and Military Families Research, Northumbria University, Newcastle, UK.
²⁸ Ophthalmology Department, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
²⁹ Academic Department of Military Surgery and Trauma, Royal Centre for Defence Medicine, Birmingham, UK.

Abstract

This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the effects of early versus delayed timing of vitrectomy after open-globe injury on visual outcomes.

MeSH terms

Eye Injuries, Penetrating* / surgery
Humans
Randomized Controlled Trials as Topic
Time Factors
Time-to-Treatment
Visual Acuity
Vitrectomy* / adverse effects
Vitrectomy* / methods