Genetics of somatoform disorders

Arch Gen Psychiatry. 1986 May;43(5):502-5. doi: 10.1001/archpsyc.1986.01800050108014.


I investigated the contribution of hereditary factors in somatoform disorders. Fourteen monozygotic and 21 dizygotic index twins and their co-twins were personally interviewed. The results showed a concordance of 29% in monozygotic and 10% in dizygotic pairs. However, similarity in childhood experience seemed to influence the concordance rates. Thus, even if somatoform disorders appear familial, the transmission may be environmental. Furthermore, the study showed a high frequency of anxiety disorders, especially generalized anxiety disorders, in the co-twins of somatoform-disordered twins.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anxiety Disorders / diagnosis
  • Anxiety Disorders / etiology
  • Anxiety Disorders / genetics
  • Diseases in Twins*
  • Female
  • Humans
  • Male
  • Manuals as Topic
  • Norway
  • Sibling Relations
  • Somatoform Disorders / diagnosis
  • Somatoform Disorders / etiology
  • Somatoform Disorders / genetics*
  • Twins, Dizygotic
  • Twins, Monozygotic