To understand how coronavirus disease 2019 vaccines impact infection risk in children <5 years, we assessed risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection from September 2022 to April 2023 in 3 cohort studies. There was no difference in risk by vaccination status. While vaccines reduce severe disease, they may not reduce SARS-CoV-2 infections in naïve young children.
Keywords: COVID-19; SARS-CoV-2; children; prior infection; vaccination.
Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society 2024.