Global Healthspan-Lifespan Gaps Among 183 World Health Organization Member States

JAMA Netw Open. 2024 Dec 2;7(12):e2450241. doi: 10.1001/jamanetworkopen.2024.50241.

Abstract

Importance: Health-adjusted life expectancy, a measure of healthy longevity, lags longevity gains, resulting in a healthspan-lifespan gap.

Objective: To quantify the healthspan-lifespan gap across the globe, investigate for sex disparities, and analyze morbidity and mortality associations.

Design, setting, and participants: This retrospective cross-sectional study used the World Health Organization (WHO) Global Health Observatory as the global data source and acquired national-level data covering all continents. The 183 WHO member states were investigated. Statistical analysis was conducted from January to May 2024.

Exposures: Data represent 2 decades of longitudinal follow-up.

Main outcomes and measures: Changes in life expectancy and health-adjusted life expectancy, as well as the healthspan-lifespan gap were quantified for all participating member states. Gap assessment was stratified by sex. Correlations of the gap with morbidity and mortality were examined.

Results: The healthspan-lifespan gap has widened globally over the last 2 decades among 183 WHO member states, extending to 9.6 years. A sex difference was observed with women presenting a mean (SD) healthspan-lifespan gap of 2.4 (0.5) years wider than men (P < .001). Healthspan-lifespan gaps were positively associated with the burden of noncommunicable diseases and total morbidity, and negatively with mortality. The US presented the largest healthspan-lifespan gap, amounting to 12.4 years, underpinned by a rise in noncommunicable diseases.

Conclusions and relevance: This study identifies growing healthspan-lifespan gaps around the globe, threatening healthy longevity across worldwide populations. Women globally exhibited a larger healthspan-lifespan gap than men.

MeSH terms

  • Aged
  • Cross-Sectional Studies
  • Female
  • Global Health* / statistics & numerical data
  • Health Status Disparities
  • Humans
  • Life Expectancy* / trends
  • Longevity
  • Male
  • Middle Aged
  • Mortality / trends
  • Retrospective Studies
  • World Health Organization*