Periampullary tumors: which ones should be resected?

Am J Surg. 1985 Jan;149(1):46-52. doi: 10.1016/s0002-9610(85)80008-8.

Abstract

Resection was carried out in 118 patients for periampullary lesions. Ninety-eight of these were adenocarcinomas and were treated by the Whipple operation, total pancreatectomy, or local resection (87 patients, 7 patients, and 4 patients, respectively). Diagnosis of pancreatic head carcinoma before resection was falsely positive in 27 percent of the patients. Mortality for radical resection was 4 percent. Five year survival for ampullary carcinoma was 32 percent, and for pancreatic head carcinoma it was 7 percent. Resection of all periampullary tumors is recommended, with the Whipple operation being the standard in most cases.

MeSH terms

  • Actuarial Analysis
  • Adenocarcinoma / diagnosis
  • Adenocarcinoma / mortality
  • Adenocarcinoma / pathology
  • Adenocarcinoma / surgery
  • Adult
  • Aged
  • Ampulla of Vater*
  • Common Bile Duct Neoplasms / diagnosis
  • Common Bile Duct Neoplasms / mortality
  • Common Bile Duct Neoplasms / pathology
  • Common Bile Duct Neoplasms / surgery*
  • Duodenal Neoplasms / diagnosis
  • Duodenal Neoplasms / mortality
  • Duodenal Neoplasms / pathology
  • Duodenal Neoplasms / surgery*
  • Duodenum / surgery
  • False Negative Reactions
  • False Positive Reactions
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pancreas / surgery
  • Pancreatectomy
  • Pancreatic Neoplasms / diagnosis
  • Pancreatic Neoplasms / mortality
  • Pancreatic Neoplasms / pathology
  • Pancreatic Neoplasms / surgery*
  • Postoperative Complications / epidemiology