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Clinical Trial
. 1985 Feb 15;55(4):707-12.
doi: 10.1002/1097-0142(19850215)55:4<707::aid-cncr2820550406>3.0.co;2-5.

A Randomized Trial of Adjuvant Chemotherapy and Immunotherapy in Stage I and Stage II Cutaneous Melanoma. An Interim Report

Clinical Trial

A Randomized Trial of Adjuvant Chemotherapy and Immunotherapy in Stage I and Stage II Cutaneous Melanoma. An Interim Report

J M Sterchi et al. Cancer. .

Abstract

Seventy patients with Stage I and II malignant melanoma were randomized to treatment with either intravenous dacarbazine alone or intravenous dacarbazine plus intradermal injection of the methanol-extracted residue of bacillus Calmette-Guerin (BCG). Analysis of treatment failed to reveal a statistically significant difference between these two forms of treatment in Stage I and II patients. It is possible that chemoimmunotherapy may increase survival in Stage II patients, but this possibility should be interpreted with caution.

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