Novel insights into Bacillus thuringiensis: Beyond its role as a bioinsecticide

Res Microbiol. 2025 Mar-Jun;176(3-4):104264. doi: 10.1016/j.resmic.2024.104264. Epub 2024 Dec 13.

Abstract

This review explores the diverse applications of Bacillus thuringiensis (Bt) beyond its traditional role as a bioinsecticide. Bt produces a variety of compounds with distinct chemical structures and biological activities. These include antimicrobial agents effective against plant pathogens and bioactive compounds that promote plant growth through the production of siderophores, hormones, and enzymes. Additionally, Bt's industrial potential is highlighted, encompassing biofuel production, bioplastics, nanoparticle synthesis, food preservation, anticancer therapies, and heavy metal bioremediation. This critical analysis emphasizes recent advancements and applications, providing insights into Bt's role in sustainable agriculture, biotechnology, and environmental management.

Keywords: Anticancer activities; Bacillus thuringiensis; Bioplastic; Food preservation; Nanoparticles biosynthesis; Plant growth-promoting bacteria (PGPB).

Publication types

  • Review

MeSH terms

  • Anti-Infective Agents / metabolism
  • Anti-Infective Agents / pharmacology
  • Bacillus thuringiensis* / chemistry
  • Bacillus thuringiensis* / metabolism
  • Bacillus thuringiensis* / physiology
  • Biodegradation, Environmental
  • Biofuels
  • Biological Control Agents*
  • Biotechnology

Substances

  • Biological Control Agents
  • Biofuels
  • Anti-Infective Agents