Patient-Reported Outcomes in Radiation Oncology

Hematol Oncol Clin North Am. 2025 Apr;39(2):347-358. doi: 10.1016/j.hoc.2024.11.005. Epub 2024 Dec 17.

Abstract

Patient-reported outcomes (PROs) assessments arguably provide the most accurate description of the patient experience, as they are directly derived from the patient without the filter of a provider. Utilizing instruments to assess PROs in radiation oncology enables a provider to measure pretreatment, on-treatment, and posttreatment symptoms. In the clinic, PROs are supplemental to physician-derived ratings that help create a complete clinical picture of a patient at a given time point to inform shared decision-making. A compilation of PROs that arise within trials, specific for given treatment regimes, will be invaluable for patients faced with choosing between options.

Keywords: CTCAE; Instrument; PRO; Patient-reported; Radiation; Radiotherapy; Survey.

Publication types

  • Review

MeSH terms

  • Humans
  • Neoplasms* / radiotherapy
  • Neoplasms* / therapy
  • Patient Reported Outcome Measures*
  • Quality of Life
  • Radiation Oncology* / methods