Use of fab fragments of digoxin-specific antibodies in the therapy of massive digoxin poisoning

Ann Emerg Med. 1985 Feb;14(2):175-8. doi: 10.1016/s0196-0644(85)81085-4.

Abstract

A case of massive digoxin ingestion with multiple arrhythmias, consisting of high grade A-V block and ventricular ectopy not responsive to lidocaine, is described. The arrhythmias ceased following administration of digoxin-specific Fab fragments. The patient improved and was transferred to the psychiatric unit.

Publication types

  • Case Reports

MeSH terms

  • Antibodies*
  • Digoxin / poisoning*
  • Female
  • Humans
  • Immunoglobulin Fab Fragments*
  • Immunotherapy*
  • Middle Aged
  • Poisoning / therapy*
  • Substance-Related Disorders / therapy

Substances

  • Antibodies
  • Immunoglobulin Fab Fragments
  • Digoxin