New pharmacological therapies for sickle cell anaemia have not been as efficacious as hoped, while widespread application of curative stem cell and gene therapies is not likely to occur soon. This situation raises the question about whether more attention now be devoted to the use of hydroxyurea in this disease.
Keywords: fetal haemoglobin; hydroxyurea; sickle cell anaemia; therapy.
Published 2024. This article is a U.S. Government work and is in the public domain in the USA. British Journal of Haematology published by British Society for Haematology and John Wiley & Sons Ltd.