Bronchopulmonary dysplasia and pulmonary insufficiency of prematurity. Lack of correlation of outcome with gas exchange abnormalities at 1 month of age

Am J Dis Child. 1985 Apr;139(4):351-4. doi: 10.1001/archpedi.1985.02140060033022.


A review of all infants admitted to the two intensive care nurseries in Seattle from July 1, 1980, through Dec 31, 1981, was performed to evaluate the outcome of infants still requiring supplemental oxygen and/or mechanical ventilation at 1 month of age. Sixty-three infants were identified. Fifty-six infants survived to at least 2 years of age, including 11 of 13 in the subgroup of infants requiring 40% or more oxygen at 1 month of age. Eight (14%) of the 56 survivors have required prolonged rehospitalization for pneumonia or other respiratory illnesses in the first two years following birth. We conclude that the degree of gas exchange impairment assessed at 1 month of age does not predict ultimate outcome from neonatal chronic lung disease.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Birth Weight
  • Bronchopulmonary Dysplasia / mortality
  • Bronchopulmonary Dysplasia / physiopathology*
  • Bronchopulmonary Dysplasia / therapy
  • Chronic Disease
  • Humans
  • Infant
  • Infant, Newborn
  • Infant, Premature, Diseases / mortality
  • Infant, Premature, Diseases / physiopathology*
  • Infant, Premature, Diseases / therapy
  • Lung Diseases / mortality
  • Lung Diseases / physiopathology*
  • Lung Diseases / therapy
  • Oxygen Inhalation Therapy
  • Prognosis
  • Pulmonary Gas Exchange*
  • Respiration, Artificial