Diltiazem and granulomatous hepatitis

Gastroenterology. 1985 May;88(5 Pt 1):1260-2. doi: 10.1016/s0016-5085(85)80089-5.

Abstract

A case of granulomatous hepatitis proven by biopsy and related to diltiazem use is described. Clinicians should be alert to the possible presence of this complication in patients who develop fever, laboratory abnormalities, or clinical evidence of hepatic injury while taking diltiazem.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Benzazepines / adverse effects*
  • Chemical and Drug Induced Liver Injury / etiology*
  • Chemical and Drug Induced Liver Injury / pathology
  • Diltiazem / adverse effects*
  • Granuloma / chemically induced*
  • Granuloma / pathology
  • Humans
  • Liver / pathology*
  • Male
  • Middle Aged

Substances

  • Benzazepines
  • Diltiazem