Hospital outbreak of NDM-producing Klebsiella pneumoniae in a surgical intensive care unit: Sink traps as the causing source of epidemic strain resurgence

Am J Infect Control. 2025 May;53(5):648-651. doi: 10.1016/j.ajic.2025.01.003. Epub 2025 Jan 11.

Abstract

We report the management of a New Delhi metallo-β-lactamase-producing Klebsiella pneumoniae outbreak in a surgical intensive care unit over 1 year. New Delhi metallo-β-lactamase-producing Enterobacterales were isolated from sink traps. The installation of new sink traps closed the outbreak. Environmental reservoirs should be considered for any persistent carbapenemase-producing Enterobacterales outbreak.

Keywords: Carbapenemase-producing Enterobacterales; Environmental reservoir; Outbreak.

MeSH terms

  • Aged
  • Carbapenem-Resistant Enterobacteriaceae* / enzymology
  • Carbapenem-Resistant Enterobacteriaceae* / isolation & purification
  • Cross Infection* / epidemiology
  • Cross Infection* / microbiology
  • Cross Infection* / prevention & control
  • Disease Outbreaks* / prevention & control
  • Drainage, Sanitary*
  • France / epidemiology
  • Hospitals, University
  • Humans
  • Intensive Care Units
  • Klebsiella Infections* / epidemiology
  • Klebsiella Infections* / microbiology
  • Klebsiella Infections* / prevention & control
  • Klebsiella pneumoniae* / enzymology
  • Klebsiella pneumoniae* / isolation & purification
  • Klebsiella pneumoniae* / pathogenicity
  • Surgery Department, Hospital
  • beta-Lactamases* / analysis

Substances

  • beta-lactamase NDM-1
  • beta-Lactamases