Single-cell transcriptomics and epigenomics point to CD58-CD2 interaction in controlling primary melanoma growth and immunity

Affiliations

• ¹ Department of Dermatology, Venereology and Allergology, University of Leipzig Medical Center, Leipzig, Germany.
• ² Interdisciplinary Center for Bioinformatics, University of Leipzig, Leipzig, Germany.
• ³ Institute for Drug Discovery, University of Leipzig Medical Center, Leipzig, Germany.
• ⁴ Bioinformatics Group, Department of Computer Science, University of Leipzig, Leipzig, Germany.
• ⁵ Department of Diagnostics, Fraunhofer Institute of Cell Therapy and Immunology (IZI), Leipzig, Germany.
• ⁶ Center for Scalable Data Analytics and Artificial Intelligence (ScaDS.AI) Dresden/Leipzig, Leipzig, Germany.
• ⁷ Department of Dermatology, University Hospital Essen, University Duisburg-Essen and German Cancer Consortium (DKTK), Partner Site Essen/Düsseldorf, Essen, Germany.