The history of (axial) spondyloarthritis has started several centuries ago. Since the end of the 19th century major achievements have been made. This historical review tries to show how closely the advances in clinical medicine in rheumatology have been related to advances made in basic sciences.
Keywords: Ankylosing spondylitis; Axial spondyloarthritis; HLA B27; Low back pain; MHC; Sacroiliac joints.
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