HLA antigens in ulcerative colitis: a study in the Sicilian population

Tissue Antigens. 1985 Jan;25(1):47-9. doi: 10.1111/j.1399-0039.1985.tb00411.x.


HLA antigens were investigated in 41 Sicilian patients with ulcerative colitis and in 151 healthy controls. Frequencies of HLA-B5 and DR2 were increased in the group of patients with ulcerative colitis whereas the DR3 antigen frequency was decreased. However the corrected p values were not significant. Thus, present results indicate that in ulcerative colitis HLA linked genetic factors play a marginal role, if any.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Colitis, Ulcerative / genetics
  • Colitis, Ulcerative / immunology*
  • Gene Frequency
  • HLA Antigens / genetics*
  • Humans
  • Italy


  • HLA Antigens