The excretion of pentoxifylline and its metabolites into human breast milk

Am J Obstet Gynecol. 1985 Apr 15;151(8):1094-7. doi: 10.1016/0002-9378(85)90391-6.

Abstract

The methylxanthine pentoxifylline enters human breast milk after a single oral dose, with a milk-plasma ratio of 0.87 +/- 0.62 at 4 hours.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Chromatography, Gas
  • Delayed-Action Preparations
  • Female
  • Humans
  • Milk, Human / metabolism*
  • Pentoxifylline / blood
  • Pentoxifylline / metabolism*
  • Theobromine / analogs & derivatives*

Substances

  • Delayed-Action Preparations
  • Theobromine
  • Pentoxifylline