Prevalence of suicidal ideation and associated factors among perinatal women living with HIV: a systematic review and meta-analysis

AIDS Care. 2025 Mar;37(3):362-371. doi: 10.1080/09540121.2025.2453664. Epub 2025 Jan 26.

Abstract

Perinatal women living with HIV face increased susceptibility to mental health challenges, including suicidal ideation (SI). This study aimed to determine the prevalence of SI among perinatal women with HIV and identify associated factors. A systematic search was done across PubMed, Embase, Scopus, ScienceDirect, and Google Scholar. Data analysis was executed using R software. Publication bias was assessed via funnel plot and Egger's test, while heterogeneity was investigated using the I2 statistic. A total of 11 studies involving 4329 participants were included. The pooled prevalence of SI was 23.4% (95% CI: 16.3-32.4). Subgroup analysis showed higher prevalence in postnatal women (36.4%) than antenatal women (27.8%), although this difference was not statistically significant. Studies employing the Edinburgh Postnatal Depression Scale reported a higher prevalence (38.9%). Studies published between 2013-2017 showed a higher prevalence (37.6%) compared to those published between 2018-2022 (18.2%). Factors associated with SI included depression during pregnancy or postpartum, unplanned pregnancy, intimate partner violence, undisclosed HIV status, lack of social support, and recent diagnosis of sexually transmitted infections other than HIV. The high prevalence of SI emphasizes the need for mental health screening and interventions. Mental health assessments should be integrated into routine antenatal and postnatal care.

Keywords: HIV/AIDS; SDG 3: good health and well-being; Suicidal ideation; perinatal women; pregnancy; suicidal behavior; suicidal thought.

Publication types

  • Systematic Review
  • Meta-Analysis

MeSH terms

  • Adult
  • Depression / epidemiology
  • Female
  • HIV Infections* / epidemiology
  • HIV Infections* / psychology
  • Humans
  • Intimate Partner Violence / psychology
  • Pregnancy
  • Pregnancy Complications, Infectious* / epidemiology
  • Pregnancy Complications, Infectious* / psychology
  • Pregnant People* / psychology
  • Prevalence
  • Risk Factors
  • Social Support
  • Suicidal Ideation*