Status epilepticus

Clin Ther. 1985;7(2):272-8.


Convulsive status epilepticus is a life-threatening disorder. Every emergency room that treats patients with this problem should have a treatment protocol prepared in advance to allow for prompt and appropriate therapy. The recommended treatment is an intravenous infusion of 20 mg/kg of phenytoin. Lorazepam or diazepam may be used to stop a convulsion in progress. If seizures persist, the second step may be an intravenous infusion of phenobarbital. If convulsions persist beyond the first hour and have not responded to the above, a barbiturate coma should be induced.

MeSH terms

  • Adult
  • Aged
  • Anticonvulsants / therapeutic use*
  • Diazepam / therapeutic use
  • Female
  • Humans
  • Male
  • Middle Aged
  • Phenobarbital / therapeutic use
  • Phenytoin / administration & dosage
  • Phenytoin / adverse effects
  • Phenytoin / therapeutic use
  • Status Epilepticus / mortality
  • Status Epilepticus / therapy*
  • Time Factors


  • Anticonvulsants
  • Phenytoin
  • Diazepam
  • Phenobarbital