Abdominal Aortic Aneurysm with Primary Cold Agglutinin Disease Treated with Endovascular Aortic Repair

Shinichi Tanaka; Takahiro Ohmine; Ryota Imanaka; Takashi Maeda

doi:10.3400/avd.cr.24-00107

Abdominal Aortic Aneurysm with Primary Cold Agglutinin Disease Treated with Endovascular Aortic Repair

Ann Vasc Dis. 2025;18(1):24-00107. doi: 10.3400/avd.cr.24-00107. Epub 2025 Jan 1.

Authors

Shinichi Tanaka¹, Takahiro Ohmine¹, Ryota Imanaka², Takashi Maeda¹

Affiliations

¹ Department of Surgery, Hiroshima Red Cross Hospital and Atomic-bomb Survivors Hospital, Hiroshima, Hiroshima, Japan.
² Department of Hepatology, Hiroshima Red Cross Hospital and Atomic-bomb Survivors Hospital, Hiroshima, Hiroshima, Japan.

Abstract

Cold agglutinin disease (CAD) is a rare and autoimmune hemolytic disorder caused by the presence of cold-reacting autoantibodies against red blood cells. An abdominal aortic aneurysm (AAA) is a potentially life-threatening condition. This report describes an 83-year-old man with AAA who was diagnosed with primary CAD 9 years before undergoing AAA surgery. The patient underwent successful endovascular aortic repair. Temporary hemolytic anemia and exacerbation of jaundice were observed postoperatively despite strict temperature control. Red blood cell and haptoglobin transfusions may prevent fatal hemolytic anemia, renal disorders, embolism, and systemic complications.

Keywords: abdominal aortic aneurysm; endovascular aortic repair; primary cold agglutinin disease.

Publication types

Case Reports