Genetic Predisposition to Coronary Artery Disease: Evaluating Statin Therapy in Elder Populations From PROSPER
JACC Adv
.
2025 Jan 8;4(2):101535.
doi: 10.1016/j.jacadv.2024.101535.
eCollection 2025 Feb.
Authors
Seung Hoan Choi
1
2
,
Robin Young
3
,
Satoshi Koyama
2
4
,
J Wouter Jukema
5
6
,
Stella Trompet
6
7
,
Ian Ford
3
,
Pradeep Natarajan
2
4
8
,
Gina M Peloso
1
Affiliations
1
Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.
2
Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.
3
Robertson Centre for Biostatistics, School of Health and Wellbeing, University of Glasgow, Glasgow, United Kingdom.
4
Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
5
Department of Cardiology, Netherlands Heart Institute, Utrecht, The Netherlands.
6
Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
7
Department of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.
8
Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
PMID:
39886309
PMCID:
PMC11780074
DOI:
10.1016/j.jacadv.2024.101535
No abstract available
Keywords:
coronary artery disease; elderly population; polygenic score; statin therapy.