CORONIS symposium 2023: Scientific and clinical frontiers in ocular surface innervation

Acta Ophthalmol. 2025 Jun;103(4):e240-e255. doi: 10.1111/aos.17450. Epub 2025 Jan 31.

Abstract

The 5th CORONIS Symposium, held during the 2023 Congress of the European Association for Vision and Eye Research (EVER), highlighted the growing importance of ocular surface innervation in eye surface disorders. This article summarises the insights and perspectives shared during the symposium, which focused on the clinical relevance of ocular surface innervation, as well as on the development of innovative diagnostic and therapeutic approaches for ocular surface pathologies linked to disturbed sensory innervation. Through robust interdisciplinary collaborations, these developments hold great potential to improve patient outcomes and quality of life.

Keywords: aniridia‐associated keratopathy; blood‐derived eye drops; chronic ocular pain; corneal nerves; dendritic cells; dry eye disease; in vivo corneal confocal microscopy; neuropathic ocular pain; ocular surface disorders; ocular surface innervation; ocular surface neurobiology; sub‐basal nerve plexus.

Publication types

  • Conference Proceedings

MeSH terms

  • Conjunctiva* / innervation
  • Cornea* / innervation
  • Corneal Diseases* / diagnosis
  • Eye Diseases*
  • Humans
  • Ophthalmology*
  • Societies, Medical