Clinical characteristics and outcomes in takotsubo syndrome -Review of insights from the InterTAK Registry

J Cardiol. 2025 Jan 30:S0914-5087(25)00009-7. doi: 10.1016/j.jjcc.2025.01.009. Online ahead of print.

Abstract

Takotsubo syndrome (TTS) is a complex cardiovascular condition characterized by transient left and/or right ventricular dysfunction in the absence of a coronary artery culprit lesion. The InterTAK registry, a large international collaborative registry, has significantly advanced our understanding of TTS. This review summarizes key findings from the InterTAK registry, including epidemiology, clinical presentation, comorbidities, outcomes, and treatment. The registry has revealed the diverse clinical spectrum of TTS, including atypical presentations, and identified various risk factors associated with adverse outcomes. The InterTAK registry has been instrumental in shaping the current understanding of TTS and will continue to guide future research and clinical practice.

Keywords: Clinical presentation; Comorbidities; Epidemiology; Outcomes; Takotsubo syndrome.

Publication types

  • Review