Pediatric Awake Craniotomy: An Educational Review

Paediatr Anaesth. 2025 Apr;35(4):270-276. doi: 10.1111/pan.15075. Epub 2025 Feb 1.

Abstract

Background: Awake craniotomies with functional cortical mapping are performed to minimize post-operative deficits from the resection of lesions adjacent to eloquent cortex. The procedure is well-established in the adult patient population and is increasingly applied to well-selected pediatric patients. A review of recent literature demonstrated that the most commonly reported anesthetic techniques were "asleep-awake-asleep" protocols that relied on propofol, remifentanil, or fentanyl.

Main article: This educational review discusses the unique challenges that face the anesthesiology and neurosurgical teams when working with the pediatric population. To further illustrate pediatric-specific considerations, a case of a 9-year-old boy who underwent a resection of a large left peri-rolandic ependymoma is presented, including his multidisciplinary pre-operative, intra-operative, and post-operative care.

Conclusion: Awake craniotomies can safely be performed in the pediatric population with appropriate patient selection, planning, and a multi-disciplinary approach.

Publication types

  • Review
  • Case Reports

MeSH terms

  • Brain Mapping / methods
  • Brain Neoplasms / surgery
  • Child
  • Craniotomy* / methods
  • Ependymoma / surgery
  • Humans
  • Male
  • Wakefulness*