Ossification of the Posterior Longitudinal Ligament in the Cervical Spine: Etiology, Clinical Presentation, and Management

JBJS Rev. 2025 Feb 4;13(2). doi: 10.2106/JBJS.RVW.24.00161. eCollection 2025 Feb 1.

Abstract

» Ossification of the posterior longitudinal ligament (OPLL) is a hyperostotic condition that results in ectopic bone formation and calcification of the posterior longitudinal ligament.» OPLL can present in any race/ethnicity but historically has been reported in the East Asian population.» OPLL predisposes patients to spinal cord injury in the setting of minor trauma.» Asymptomatic patients typically can be managed nonoperatively. Surgical treatment is reserved for patients presenting with myelopathy and worsening radiculopathy that has not responded to conservative treatment.» The decision to use anterior, posterior, or combined anterior-posterior approaches should be an individualized decision that considers the degree of OPLL pathology, K-line imaging findings, and other patient-specific risk factors.

Publication types

  • Review

MeSH terms

  • Cervical Vertebrae* / diagnostic imaging
  • Humans
  • Ossification of Posterior Longitudinal Ligament* / diagnosis
  • Ossification of Posterior Longitudinal Ligament* / diagnostic imaging
  • Ossification of Posterior Longitudinal Ligament* / etiology
  • Ossification of Posterior Longitudinal Ligament* / therapy