Abstract
In vivo effects of glucocorticoids on rat serum corticosterone level were investigated by using a simple and convenient HPLC-UV detection method. Serum corticosterone level was decreased by a single injection of hydrocortisone, methylprednisolone, betamethasone, dexamethasone or fluocinonide.
MeSH terms
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Animals
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Betamethasone / pharmacology
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Chromatography, High Pressure Liquid
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Corticosterone / blood*
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Dexamethasone / pharmacology
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Fluocinonide / pharmacology
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Glucocorticoids / pharmacology*
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Hydrocortisone / pharmacology
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Male
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Methylprednisolone / pharmacology
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Rats
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Rats, Inbred Strains
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Spectrophotometry, Ultraviolet
Substances
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Glucocorticoids
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Fluocinonide
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Dexamethasone
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Betamethasone
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Corticosterone
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Hydrocortisone
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Methylprednisolone