In vivo effects of glucocorticoids on serum corticosterone levels in rats

Res Commun Chem Pathol Pharmacol. 1985 Mar;47(3):441-4.

Abstract

In vivo effects of glucocorticoids on rat serum corticosterone level were investigated by using a simple and convenient HPLC-UV detection method. Serum corticosterone level was decreased by a single injection of hydrocortisone, methylprednisolone, betamethasone, dexamethasone or fluocinonide.

MeSH terms

  • Animals
  • Betamethasone / pharmacology
  • Chromatography, High Pressure Liquid
  • Corticosterone / blood*
  • Dexamethasone / pharmacology
  • Fluocinonide / pharmacology
  • Glucocorticoids / pharmacology*
  • Hydrocortisone / pharmacology
  • Male
  • Methylprednisolone / pharmacology
  • Rats
  • Rats, Inbred Strains
  • Spectrophotometry, Ultraviolet

Substances

  • Glucocorticoids
  • Fluocinonide
  • Dexamethasone
  • Betamethasone
  • Corticosterone
  • Hydrocortisone
  • Methylprednisolone