Microsurgical versus complex physical decongestive therapy for chronic breast cancer-related lymphoedema

Yvonne Haas; Olivia P Williams; Jaume Masia; Gemma Pons; Erin M Taylor; Maria C Katapodi; Daniel Staub; Steffen U Eisenhardt; Giuseppe Visconti; Benedetto Longo; Jan Plock; Florian Jung; Eduardo Gonzalez; Benedict Kaiser; Lea Zehnpfennig; Julia Stoffel; Florian S Halbeisen; Christian Appenzeller-Herzog; Laura Hilbig-Vlatten; Yvette Stoel; Raymund E Horch; Maria Mani; Karin Ribi; Joshua Vorstenbosch; Kathryn V Isaac; Shan Shan Qiu; Björn Behr; Lars G Hemkens; Nicole Lindenblatt; Dirk J Schaefer; Katrin Seidenstuecker; Yves Harder; Christoph R Hirche; Walter P Weber; Elisabeth A Kappos

doi:10.1002/14651858.CD016019

Microsurgical versus complex physical decongestive therapy for chronic breast cancer-related lymphoedema

Cochrane Database Syst Rev. 2025 Feb 13;2(2):CD016019. doi: 10.1002/14651858.CD016019.

Authors

Yvonne Haas^{1

2}, Olivia P Williams², Jaume Masia³, Gemma Pons³, Erin M Taylor⁴, Maria C Katapodi^{5

6}, Daniel Staub⁷, Steffen U Eisenhardt⁸, Giuseppe Visconti⁹, Benedetto Longo¹⁰, Jan Plock¹¹, Florian Jung¹², Eduardo Gonzalez¹³, Benedict Kaiser¹, Lea Zehnpfennig¹⁴, Julia Stoffel^{1

2}, Florian S Halbeisen¹⁵, Christian Appenzeller-Herzog¹⁶, Laura Hilbig-Vlatten¹⁷, Yvette Stoel¹⁸, Raymund E Horch¹⁹, Maria Mani²⁰, Karin Ribi²¹, Joshua Vorstenbosch²², Kathryn V Isaac²³, Shan Shan Qiu²⁴, Björn Behr²⁵, Lars G Hemkens^{5

26

27}, Nicole Lindenblatt²⁸, Dirk J Schaefer^{1

2}, Katrin Seidenstuecker²⁹, Yves Harder^{30

31}, Christoph R Hirche³², Walter P Weber^{2

33}, Elisabeth A Kappos^{1

2}

Affiliations

¹ Department of Plastic, Reconstructive, Aesthetic and Hand Surgery, University Hospital Basel, Basel, Switzerland.
² University of Basel, Basel, Switzerland.
³ Department of Plastic Surgery, Hospital de la Santa Creu i Sant Pau Universitat Autònoma de Barcelona, Barcelona, Spain.
⁴ Division of Plastic and Reconstructive Surgery, Department of Surgery, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachussetts, USA.
⁵ Department of Clinical Research, University of Basel, Basel, Switzerland.
⁶ Patient Advocacy Group, Oncoplastic Breast Consortium, Basel, Switzerland.
⁷ Department of Angiology, University Hospital Basel, Basel, Switzerland.
⁸ Department of Plastic and Hand Surgery, University of Freiburg Medical Center, Medical Faculty of the University of Freiburg, Freiburg, Germany.
⁹ Department of Woman and Child Health and Public Health, Division of Plastic Surgery, Fondazione Policlinico Universitario "A Gemelli" IRCCS, Rome, Italy.
¹⁰ Department of surgical sciences - Division of Plastic Surgery, Tor Vergata University Hospital, Rome, Italy.
¹¹ Department of Plastic Surgery and Hand Surgery, Cantonal Hospital Aarau, Aarau, Switzerland.
¹² Department of Plastic and Hand Surgery, Cantonal Hospital of Winterthur, Winterthur, Switzerland.
¹³ Division of Oncoplastic Surgery, Oncologic Institute Instituto de Oncología Ángel H Roffo, Buenos Aires British Hospital, University of Buenos Aires, Buenos Aires, Argentina.
¹⁴ University of Duisburg-Essen, Essen, Germany.
¹⁵ Surgical Outcome Research Center, University Hospital Basel, Basel, Switzerland.
¹⁶ University Medical Library, University of Basel, Basel, Switzerland.
¹⁷ Albert-Ludwigs-University Freiburg, Freiburg, Germany.
¹⁸ Institute of Therapies and Rehabilitation, Division of Physiotherapy, Cantonal Hospital of Winterthur, Winterthur, Switzerland.
¹⁹ Department of Plastic and Hand Surgery, University Hospital Erlangen, Erlangen, Germany.
²⁰ Department of Plastic and Maxillofacial Surgery, Uppsala University Hospital, Uppsala, Sweden.
²¹ Quality of Life Office, International Breast Cancer Study Group, a division of ETOP IBCSG Partners Foundation, Bern, Careum School of Health, part of the Kalaidos University of Applied Sciences, Zürich, Switzerland.
²² Department of Plastic and Reconstructive Surgery, McGill University Health Center, Montreal, Quebec, Canada.
²³ Division of Plastic Surgery, University of British Columbia, Vancouver, Canada.
²⁴ Department of Plastic, Reconstructive and Hand Surgery, Maastricht University Medical Centre, Maastricht, Netherlands.
²⁵ Department of Plastic,- Reconstructive and Aesthetic Surgery, Kliniken Essen-Mitte (KEM), Essen, Germany.
²⁶ Pragmatic Evidence Lab, Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel and University of Basel, Basel, Switzerland.
²⁷ Meta-Research Innovation Center at Stanford (METRICS), Stanford University, Stanford CA, USA.
²⁸ Department of Plastic and Hand Surgery, University Hospital Zurich, Zurich, Switzerland.
²⁹ Department of Plastic Surgery, Sana Hospitals Düsseldorf, Düsseldorf, Germany.
³⁰ Department of Plastic, Reconstructive and Aesthetic Surgery and Hand Surgery, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.
³¹ Faculty of Biology and Medicine, University of Lausanne (UNIL), Lausanne, Switzerland.
³² Department of Plastic Surgery, Hand and Reconstructive Microsurgery, Hand Trauma and Replantation Centre, BG Unfallklinik Frankfurt am Main, Frankfurt, Germany.
³³ Breast Center, University Hospital Basel, Basel, Switzerland.

Abstract

This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the effects of microsurgery versus complex physical decongestive therapy in people with chronic breast cancer-related lymphoedema.

Publication types

Systematic Review

MeSH terms

Breast Cancer Lymphedema* / complications
Breast Cancer Lymphedema* / psychology
Breast Cancer Lymphedema* / therapy
Chronic Disease / therapy
Compression Bandages
Controlled Clinical Trials as Topic
Female
Humans
Lipectomy / adverse effects
Lipectomy / methods
Microsurgery* / methods
Physical Therapy Modalities*
Quality of Life
Skin Care / methods
Systematic Reviews as Topic
Treatment Outcome