A Randomized Open-Labelled Clinical Study on the Efficacy of Polyherbal Oral and Topical Unani Formulations (Majoon and Tila) Versus Tentex Forte and Himcolin in Erectile Dysfunction

Altern Ther Health Med. 2025 Jul;31(4):29-33.

Abstract

Background: Erectile Dysfunction (ED) is a problem of achieving or maintaining a firm erection for satisfactory sexual intercourse.

Objective: To compare the efficacy of polyherbal oral and topical Unani formulations (Majoon/Electuary and Tila/liniment) versus Tentex Forte and Himcolin in Erectile dysfunction.

Methods: This study was a comparative clinical trial conducted on 36 patients, with n = 18 in each test and control group. The test group was treated with polyherbal oral formulation (Majoon) 1 tsp twice daily and few drops of Tila locally. The control group received two capsules of Tentex Forte twice daily, with a few drops of Himcolin gel locally. Likewise, both groups were treated for 28 days. Study outcomes viz. difficulty in achieving and maintaining penile erections, and International Index of Erectile Function-15 score were assessed before and at the end of the study. Student t tests, Mc Nemars, and chi-square tests were used for data analysis.

Results: The findings of this study suggest that there is a highly significant effect of either intervention on difficulty in achieving and maintaining penile erection (P < .001) and IIEF-15 scores (P < .001). However, no significant difference was observed between the two groups (P = .15), which signifies that both interventions have a comparable effect on erectile dysfunction.

Conclusion: It can be concluded that polyherbal Unani formulation Majoon 7g twice orally and a few drops of Tila locally are equally effective as Tentex Forte and Himcolin in managing erectile dysfunction.

Publication types

  • Randomized Controlled Trial
  • Comparative Study

MeSH terms

  • Administration, Oral
  • Administration, Topical
  • Adult
  • Erectile Dysfunction* / drug therapy
  • Humans
  • Male
  • Medicine, Unani* / methods
  • Middle Aged
  • Penile Erection / drug effects
  • Phytotherapy* / methods
  • Plant Extracts* / administration & dosage
  • Plant Extracts* / therapeutic use
  • Treatment Outcome

Substances

  • Plant Extracts