Heterogeneity of Primary Outcomes in Large Atherosclerotic Cardiovascular Disease Trials Published in Prominent Medical Journals

JAMA Intern Med. 2025 Apr 1;185(4):464-466. doi: 10.1001/jamainternmed.2024.7694.

Authors

Daniel Shepshelovich¹, Dafna Yahav^{2

3}, Danielle R Rome¹, Hadar Goldvaser⁴, Ilan Richter¹, Emilia A Hermann¹, R Graham Barr^{1

5}

Affiliations

¹ Department of Medicine, Columbia University Irving Medical Center, New York, New York.
² Infectious Diseases Unit, Sheba Medical Center, Ramat-Gan, Israel.
³ Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
⁴ Memorial Sloan Kettering Cancer Center, New York, New York.
⁵ Department of Epidemiology, Columbia University Irving Medical Center, New York, New York.

No abstract available

Plain language summary

This cohort study examines heterogeneity in primary end points reported by randomized clinical trials of atherosclerotic cardiovascular disease published in prominent medical journals.

Grants and funding

P30 CA008748/CA/NCI NIH HHS/United States