Withdrawal: RNA Silencing Identifies PDE4D5 as the Functionally Relevant cAMP Phosphodiesterase Interacting with βArrestin to Control the Protein Kinase A/AKAP79-mediated Switching of the β2-Adrenergic Receptor to Activation of ERK in HEK293B2 Cells

Martin J Lynch; George S Baillie; Ahmed Mohamed; Xiang Li; Charlotte Maisonneuve; Enno Klussmann; Gino van Heeke; Miles D Houslay

doi:10.1016/j.jbc.2024.108141

Withdrawal: RNA Silencing Identifies PDE4D5 as the Functionally Relevant cAMP Phosphodiesterase Interacting with βArrestin to Control the Protein Kinase A/AKAP79-mediated Switching of the β₂-Adrenergic Receptor to Activation of ERK in HEK293B2 Cells

J Biol Chem. 2025 Feb 16;301(3):108141. doi: 10.1016/j.jbc.2024.108141. Online ahead of print.

Authors

Martin J Lynch, George S Baillie, Ahmed Mohamed, Xiang Li, Charlotte Maisonneuve, Enno Klussmann, Gino van Heeke, Miles D Houslay

PMID: 39961194
DOI: 10.1016/j.jbc.2024.108141

Abstract

The Journal concluded that the second and third lanes of Figure 4B had been derived from the same source image. Raw data was not available to address the Journal's concerns. The authors have decided to withdraw the article.

Publication types

Retraction Notice