Biomechanical and radiographic advantages of double-level osteotomy over single-level osteotomy for medial knee osteoarthritis with double-level deformity: A retrospective analysis

Clin Biomech (Bristol). 2025 Mar:123:106469. doi: 10.1016/j.clinbiomech.2025.106469. Epub 2025 Feb 21.

Abstract

Background: Double-level osteotomy is hypothesized to provide superior biomechanical outcomes compared to single-level osteotomy for medial knee osteoarthritis with double-level deformity. However, its advantages remain underexplored.

Methods: This retrospective study analyzed 20 knees treated with medial open wedge high tibial osteotomy alone or combined with lateral closed wedge distal femoral osteotomy. Patients were categorized into three groups: Single-level osteotomy for single deformity, single-level osteotomy for double deformity, and double-level osteotomy for double deformity. Radiographic parameters, including Hip-Knee-Ankle angle, mechanical lateral distal femoral angle, medial proximal tibial angle and joint line convergence angle, and gait biomechanics using nine-axis inertial measurement units were evaluated pre- and postoperatively.

Findings: The postoperative mechanical lateral distal femoral angle was better corrected in the double-level osteotomy for double deformity group compared to the single-level osteotomy for double deformity group (P = 0.012). Peak thigh varus acceleration was significantly reduced in both the double-level osteotomy for double deformity and single-level osteotomy for single deformity groups (P = 0.014), but not in the single-level osteotomy for double deformity group. No significant differences were observed in medial proximal tibial angle among groups.

Interpretation: Double-level osteotomy demonstrated superior biomechanical and radiographic outcomes in medial knee osteoarthritis with double-level deformity, emphasizing its role in mitigating joint line obliquity and in optimizing dynamic knee stability.

Keywords: Acceleration; Double level osteotomy; Inertial measurement unit; Joint line obliquity; Knee osteoarthritis; Osteotomy around the knee.

MeSH terms

  • Aged
  • Biomechanical Phenomena
  • Female
  • Femur / diagnostic imaging
  • Femur / surgery
  • Gait
  • Humans
  • Knee Joint / diagnostic imaging
  • Knee Joint / physiopathology
  • Knee Joint / surgery
  • Male
  • Middle Aged
  • Osteoarthritis, Knee* / diagnostic imaging
  • Osteoarthritis, Knee* / physiopathology
  • Osteoarthritis, Knee* / surgery
  • Osteotomy* / methods
  • Radiography
  • Retrospective Studies
  • Tibia / diagnostic imaging
  • Tibia / physiopathology
  • Tibia / surgery
  • Treatment Outcome