IgA nephropathy is not a rare disease in the United Kingdom

Nephron. 1985;40(2):180-4. doi: 10.1159/000183457.


A retrospective analysis of all renal biopsies performed in the Grampian Region of Scotland during 1977-1980 revealed that IgA nephropathy was the most frequently encountered glomerular lesion. The commonest indications for renal biopsy were the presence of asymptomatic urinary abnormalities (90/184; 48.9%) especially asymptomatic haematuria (42/184; 22.8%). A histological diagnosis was made in 36 of the 42 patients presenting with asymptomatic haematuria (85.7%); 16 of the 26 cases of IgA nephropathy presented in this way. Overall, IgA nephropathy was detected in 14.1% of all biopsies and accounted for 21.8% of primary glomerular diseases. This study indicates that IgA nephropathy is apparently more common in Grampian than elsewhere in the United Kingdom. However, it is suggested that this does not represent a true variation in the prevalence of the condition; IgA nephropathy is probably a common cause of haematuria in the United Kingdom.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Biopsy
  • Child
  • England
  • Female
  • Glomerulonephritis, IGA / epidemiology*
  • Hematuria / pathology
  • Humans
  • Hypertension / complications
  • Kidney / pathology
  • Kidney Glomerulus / pathology
  • Male
  • Middle Aged
  • Sex Factors