Oxygen tension in human tumors: in vivo mapping using CT-guided probes

Radiology. 1985 Jul;156(1):211-4. doi: 10.1148/radiology.156.1.4001408.

Abstract

The role of oxygen in tumor response to therapy has been studied for several decades. We describe a technique that allows in vivo measurement of oxygen in tumors using computed tomography to guide probes. In the evaluation of 16 tumors, oxygen tensions were found to be substantially lower than surrounding tissue and varied nonrandomly. This technique has allowed construction of detailed tumor oxygen level maps.

MeSH terms

  • Adult
  • Aged
  • Electrodes
  • Female
  • Humans
  • Lymphatic Metastasis
  • Male
  • Middle Aged
  • Neoplasms / analysis*
  • Neoplasms / blood supply
  • Neoplasms / diagnostic imaging
  • Oxygen / analysis*
  • Oxygen / physiology
  • Tomography, X-Ray Computed*

Substances

  • Oxygen