"First-in-human" totally robotic orthotopic heart transplant

J Heart Lung Transplant. 2025 Jun;44(6):1000-1003. doi: 10.1016/j.healun.2025.02.1685. Epub 2025 Feb 25.

Abstract

Importance: Traditionally, heart transplantation surgery requires a median sternotomy due to the perceived complexity of a large organ replacement. Whether an alternative minimally invasive approach to perform a successful heart transplant can be accomplished remains uncertain.

Objective: To develop a safe and effective technique for totally robotic heart transplantation.

Design: Using a multidisciplinary team, technical timed training using the robot-assisted approach was accomplished on multiple cadavers. Importantly, practice to limit the donor organ ischemic time to ensure patient safety was deemed essential, and once readiness was achieved, an in-vivo operation was undertaken.

Setting: Academic cardiac surgical unit of King Faisal Specialist Hospital and Research Centre, Riyadh (Saudi Arabia).

Participant: A 16-year-old boy with refractory biventricular heart failure caused by a nonischemic dilated cardiomyopathy MAIN OUTCOME: A successful totally robotic heart transplant, with a short ischemic time, mechanical ventilation <24 hours, rapid patient mobilization, and reduced postoperative pain and hospital duration of stay.

Keywords: heart transplant; minimal invasive cardiac surgery; robotic cardiac surgery.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Cardiomyopathy, Dilated* / complications
  • Cardiomyopathy, Dilated* / surgery
  • Heart Failure* / etiology
  • Heart Failure* / surgery
  • Heart Transplantation* / methods
  • Humans
  • Male
  • Robotic Surgical Procedures* / methods