Four-Step Synthesis of 3-Allyl-2-(allyloxy)-5-bromoaniline from 2-Allylphenol

Molbank. 2024 Mar;2024(1):M1773. doi: 10.3390/m1773. Epub 2024 Feb 7.

Abstract

This communication reports a four-step protocol to produce 3-allyl-2-(allyloxy)-5-bromoaniline 5 from commercially available 2-allylphenol. The synthetic steps used were nitration, selective bromination, allylation, and reduction of the nitro group.

Keywords: 2-allylphenol; allylic ether; aniline; nitration.